Tag: anticholinergic burden
tricyclic antidepressants
anticholinergic burden
cognitive decline
cardiac risks
amitriptyline
Anticholinergic Burden with Tricyclic Antidepressants: Cognitive and Cardiac Risks
Tricyclic antidepressants like amitriptyline carry high anticholinergic burden, increasing risks of cognitive decline and dangerous heart rhythm changes. Safer alternatives exist, and many side effects can be reversed by switching medications.
December 15 2025