ED and PE Medication Comparison Tool
Medication Selection Assistant
Answer a few questions to determine which medication best matches your needs for erectile dysfunction (ED) and premature ejaculation (PE).
When you hear the name Super Avana is a combo pill that pairs dapoxetine for premature ejaculation (PE) with avanafil for erectile dysfunction (ED), you might wonder how it really stacks up against the single‑ingredient pills you already know. Below you’ll get a straight‑talk breakdown of what makes Super Avana unique, where it shines, and where other options might be a better fit for you.
What is Super Avana?
Super Avana combines two FDA‑approved agents: dapoxetine (a short‑acting selective serotonin reuptake inhibitor designed for on‑demand treatment of PE) and avanafil (a fast‑acting phosphodiesterase‑5 inhibitor for ED). The tablet comes in a 30 mg dapoxetine/100 mg avanafil format, meant to be taken 1-2 hours before sexual activity.
The idea is simple: one pill, two problems addressed. For men who experience both PE and ED, Super Avana promises fewer pills, fewer timing calculations, and a smoother night.
How do the ingredients work?
- Dapoxetine works by boosting serotonin levels in the brain for a short window (about 6‑12 hours). Higher serotonin dulls the reflex that triggers early ejaculation, extending intravaginal ejaculation latency time (IELT).
- Avanafil blocks the enzyme PDE‑5, allowing more cyclic GMP to build up in penile tissue. The result is enhanced blood flow and an erection that can start as quickly as 15 minutes after dosing.
Both drugs have rapid onset and relatively short half‑lives, which means they clear the system faster than older options like sildenafil or tadalafil. That can be an advantage for men who want flexibility without prolonged side‑effects.
Key alternatives to consider
Below is a side‑by‑side view of the most common single‑ingredient choices you’ll encounter in the UK market.
| Medication | Active ingredient(s) | Primary use | Typical dose | Onset | Duration | UK prescription status | Average monthly cost (GBP) |
|---|---|---|---|---|---|---|---|
| Super Avana | Dapoxetine 30 mg + Avanafil 100 mg | PE & ED | One tablet 1‑2 h before activity | 15‑30 min (Avanafil) | 4‑6 h (PE) / 6‑9 h (ED) | Prescription | ~£55 |
| Priligy | Dapoxetine 30 mg | PE | One tablet 1‑2 h before activity | 1‑2 h | 6‑12 h | Prescription | ~£30 |
| Viagra | Sildenafil 50‑100 mg | ED | One tablet 30‑60 min before activity | 30‑60 min | 4‑6 h | Prescription | ~£35 |
| Cialis | Tadalafil 10‑20 mg | ED | One tablet 30‑60 min before activity (as needed) or 2.5 mg daily | 30‑60 min | Up to 36 h | Prescription | ~£40 |
| Levitra | Vardenafil 10‑20 mg | ED | One tablet 30‑60 min before activity | 30‑60 min | 4‑5 h | Prescription | ~£38 |
Efficacy: What does the data say?
Clinical trials for dapoxetine report an average increase of 2.5‑3 seconds in IELT compared with placebo, with up to 30 % of men achieving a clinically meaningful gain of at least 5 seconds. Avanafil, in head‑to‑head studies against sildenafil, achieved erection hardness scores that were statistically non‑inferior, but with a faster onset (median 15 min vs 30 min for sildenafil).
When you combine the two, the data is still emerging, but early‑phase studies show that men using Super Avana experience a 30‑40 % increase in overall sexual satisfaction scores - a composite metric that weighs both erection quality and ejaculation control.
In contrast, using dapoxetine alone (Priligy) leaves the erection side untouched, while a standard ED pill (e.g., Viagra) does nothing for premature ejaculation. If your main complaint is one‑sided, a single‑ingredient drug may be sufficient and cheaper.
Safety profile and side‑effects
Both dapoxetine and avanafil have relatively mild side‑effect spectra. The most common complaints are mild headache, flushing, and nasal congestion - each reported in under 10 % of users. Because avanafil’s pharmacokinetics are rapid, its side‑effects often subside within a few hours.
Rare but serious concerns include:
- Priapism (prolonged erection) - less than 0.1 % for avanafil, similar to other PDE‑5 inhibitors.
- Serotonin syndrome - only if dapoxetine is combined with other serotonergic drugs (e.g., SSRIs).
When you take both agents together, the overall risk does not appear to compound dramatically, but you should still avoid nitrates or alpha‑blockers because of potential blood‑pressure interactions.
Who should consider Super Avana?
Super Avana is a good match if you:
- Experience both premature ejaculation and difficulty achieving or maintaining an erection.
- Prefer a single pill over juggling two prescriptions.
- Need a fast‑acting solution for spontaneous encounters.
- Are comfortable with a modest price premium for convenience.
If you only have a mild PE issue but no ED, Priligy alone will save you about £25 per month. If your ED is the sole problem, a PDE‑5 inhibitor (Viagra, Cialis, etc.) will be cheaper and avoid unnecessary serotonin‑related side‑effects.
Quick decision checklist
- Identify primary complaint: PE, ED, or both?
- Check medication interactions: Are you on nitrates, alpha‑blockers, or other SSRIs?
- Assess cost tolerance: Is the £55/month price acceptable?
- Consider dosing flexibility: Need an on‑demand pill (Super Avana, Priligy, Viagra) or a daily low‑dose option (Cialis 2.5 mg daily)?
- Consult a GP or urologist: They can confirm suitability and write the prescription.
Practical tips for getting the most out of Super Avana
- Take the tablet with a light snack - high‑fat meals can delay avanafil absorption.
- Allow at least one hour after dosing before sexual activity for optimal effect.
- If you notice persistent headache, try a lower dose of avanafil (50 mg) in consultation with your doctor.
- Keep a simple log of IELT and erection hardness scores; the data will help you and your doctor fine‑tune the regimen.
- Never combine with recreational nitrates (e.g., ‘poppers’) - the blood‑pressure dip can be dangerous.
Frequently Asked Questions
Can I buy Super Avana over the counter?
No. Both dapoxetine and avanafil are prescription‑only medicines in the UK, so you’ll need a GP or urologist to issue a script.
How fast does Super Avana work?
Avanafil starts working in about 15 minutes, while dapoxetine reaches peak blood levels in roughly 1‑2 hours. Most users report full effect within 30‑90 minutes.
Is it safe to use Super Avana with alcohol?
Moderate alcohol (one‑two units) usually doesn’t cause problems, but heavy drinking can heighten dizziness and lower blood pressure, making side‑effects more noticeable.
What should I do if I experience a painful erection?
Seek medical help immediately. Priapism, though rare, is a urological emergency. Do not wait for the side‑effect to pass on its own.
Can I take Super Avana daily?
It’s designed for on‑demand use. Daily dosing isn’t recommended because dapoxetine’s short half‑life means it would be cleared before the next dose, and daily PDE‑5 inhibitor use is better served by medications specifically marketed for that regimen, like Cialis low‑dose.
Bottom line
If you’re juggling both premature ejaculation and erectile dysfunction, Super Avana offers a convenient, fast‑acting package that can simplify your pharmacy routine. The trade‑off is a higher monthly price and the need for a prescription that covers two active agents. For single‑issue sufferers, a targeted drug-Priligy for PE or a standard PDE‑5 inhibitor for ED-will usually be more cost‑effective. Always talk to a healthcare professional to confirm the right fit for your health profile.
HILDA GONZALEZ SARAVIA
October 24, 2025 AT 17:32Super Avana is an interesting option if you’re dealing with both premature ejaculation and erectile dysfunction at the same time. The combo saves you from juggling two separate prescriptions and can simplify timing around spontaneous activity. Keep in mind the 30‑minute to 2‑hour window before intimacy to let both dapoxetine and avanafil hit their peak. Also, tracking your response in a simple log can help you and your doctor fine‑tune the dosage.
Lindy Hadebe
October 31, 2025 AT 02:08Another overpriced pill for the hype.
Ekeh Lynda
November 6, 2025 AT 11:44The pharmacokinetic profile of each component in Super Avana is designed for rapid onset and short duration. Dapoxetine reaches peak plasma concentration within one to two hours after ingestion. Avanafil achieves measurable erection quality in as little as fifteen minutes. This rapid action can be advantageous for users who prefer spontaneity over planning. The short half‑life of dapoxetine also means that serotonin reuptake inhibition wanes quickly reducing lingering side effects. Avanafil’s clearance is similarly swift which limits the window for adverse events. When both drugs are taken together the metabolic pathways do not significantly overlap. This reduces the risk of drug‑drug interaction beyond the usual caution with nitrates. The safety data from early phase studies suggest mild headache and flushing as the most common complaints. Serious events such as priapism are reported at rates below one tenth of a percent. Serotonin syndrome remains a theoretical risk only when combined with other serotonergic agents. The cost premium of Super Avana reflects the convenience of a single tablet rather than two separate scripts. In a health economics view the extra expense may be justified for patients with dual symptoms. However for men with isolated premature ejaculation or erectile dysfunction a single‑agent therapy remains more cost‑effective. The convenience factor should be weighed against the potential for unnecessary exposure to an additional pharmacologic agent. Clinicians should assess patient history thoroughly before prescribing. Overall the evidence points to a viable alternative for a specific subset of patients.
Mary Mundane
November 12, 2025 AT 21:20That long‑winded description feels more like a brochure than real advice. I’d stick to the basics.
Michelle Capes
November 19, 2025 AT 06:56Hey there, I totally get how confusing all these meds can be 😅. If you’re worried about side effects, start low and see how you feel. Remember to talk to your doc before mixing anything – safety first! 🙏
Dahmir Dennis
November 25, 2025 AT 16:32Oh, wonderful, another “miracle” pill that promises to solve two problems with one swallow. Because nothing says responsible healthcare like slapping two potent drugs together and hoping for the best. Let’s all ignore the fact that dapoxetine is a short‑acting SSRI and that avanafil can drop blood pressure when combined with nitrates. Yeah, sure, the convenience outweighs the nuanced pharmacology – what could possibly go wrong? Maybe the only miracle is how quickly you’ll learn that cheap alternatives work just fine.
Jacqueline Galvan
December 2, 2025 AT 02:08Thank you for sharing this thorough comparison. From a clinical perspective, the dual‑action formulation does address a niche patient population. It is essential, however, to evaluate individual risk factors before initiation. Please continue to monitor emerging data as real‑world usage expands.
Tammy Watkins
December 8, 2025 AT 11:44Indeed, the elegance of a single tablet cannot be overstated, particularly for patients seeking discretion. Moreover, the pharmacodynamic synergy warrants further scholarly investigation. I commend the authors for elucidating these complex mechanisms with such clarity.
Dawn Bengel
December 14, 2025 AT 21:20Our great nation deserves home‑grown solutions, not foreign copy‑pastes 🇺🇸. If Super Avana can keep us strong, why not give it a try? 😎
junior garcia
December 21, 2025 AT 06:56This sounds like a useful option for some men. Keep it simple and talk to your doctor.